NHPC License Exam Preparation: BMLT MCQs ( Free )

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NHPC License Exam Preparation: BMLT MCQs

Prepare for your NHPC License Exam with our comprehensive collection of BMLT MCQs. Practice important questions, strengthen your lab concepts, and boost your confidence to ace the NHPC licensing exam for Medical Laboratory Technologists.

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Category: NHPC , BMLT

1. Type I hypersensitivity is mediated by :

a) IgG and complement

b) T cells

c) IgE and mast cells

d) Immune complexes

2 / 29

Category: NHPC , BMLT

2. Passive immunity is acquired through :

a) Vaccination

b) Maternal IgG crossing placenta

c) Natural infection

d) Memory B-cell activation

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Category: NHPC , BMLT

3. The classical complement pathway is activated by :

a) Mannose-binding lectin

b) Bacterial lipopolysaccharides

c) Antigen-antibody complexes

d) Alternate pathway factors

4 / 29

Category: NHPC , BMLT

4. Which test detects HIV antibodies using enzyme-linked immunosorbent assay ?

a) Western blot

b) ELISA

c) Immunofluorescence

d) Agglutination

5 / 29

Category: NHPC , BMLT

5. Which cytokine is critical for antiviral defense ?

a) IL-4

b) TNF-α

c) IFN-γ

d) IL-10

6 / 29

Category: NHPC , BMLT

6. Dysplasia in epithelial tissues refers to :

a) Reversible cellular adaptation

b) Increased cell division

c) Loss of uniformity and architectural orientation

d) Chronic inflammation

7 / 29

Category: NHPC , BMLT

7. A "shift to the left" in WBC differential refers to :

a) Increased lymphocytes

b) Increased eosinophils

c) Increased immature neutrophils

d) Decreased monocytes

8 / 29

Category: NHPC , BMLT

8. Which antibody class is predominantly involved in mucosal immunity ?

a) IgG

b) IgE

c) IgM

d) IgA

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Category: NHPC , BMLT

9. Graves' disease is caused by autoantibodies targeting :

a) Insulin receptors

b) TSH receptors

c) Glutamic acid decarboxylase

d) Intrinsic factor

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Category: NHPC , BMLT

10. Which of the following is a feature of Barrett’s esophagus ?

a) Squamous metaplasia

b) Intestinal metaplasia

c) Necrotizing granulomas

d) Hyaline arteriosclerosis

11 / 29

Category: NHPC , BMLT

11. Which is a critical value for blast cells in peripheral blood ?

a) >1%

b) >5%

c) >10%

d) >20%

12 / 29

Category: NHPC , BMLT

12. Granulomatous inflammation is a key feature of :

a) Tuberculosis

b) Acute appendicitis

c) Myocardial infarction

d) Osteoporosis

13 / 29

Category: NHPC , BMLT

13. The principle of the cyanmethemoglobin method is used to estimate :

a) ESR

b) Platelet count

c) Hemoglobin

d) Reticulocyte count

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Category: NHPC , BMLT

14. Which staining technique is used to identify amyloid deposits in tissues ?

a) Periodic Acid-Schiff (PAS)

b) Masson’s Trichrome

c) Congo Red

d) Ziehl-Neelsen

15 / 29

Category: NHPC , BMLT

15. Which tumor shows "rosettes" as a histological feature ?

a) Meningioma

b) Neuroblastoma

c) Chondrosarcoma

d) Leiomyoma

16 / 29

Category: NHPC , BMLT

16. Which histological feature is diagnostic of Hodgkin’s lymphoma ?

a) Touton giant cells

b) Reed-Sternberg cells

c) Schiller-Duval bodies

d) Verocay bodies

17 / 29

Category: NHPC , BMLT

17. The principle of ELISA involves :

a) DNA replication

b) Antigen-antibody reaction using labeled enzymes

c) Bacterial culture amplification

d) RNA transcription

18 / 29

Category: NHPC , BMLT

18. Which cell is primarily responsible for antigen presentation in adaptive immunity ?

a) Neutrophil

b) Basophil

c) Dendritic cell

d) Eosinophil

19 / 29

Category: NHPC , BMLT

19. The Westergren method measures :

a) Hemoglobin

b) Bleeding time

c) ESR (Erythrocyte Sedimentation Rate)

d) Prothrombin time

20 / 29

Category: NHPC , BMLT

20. Which of the following is a characteristic histological feature of squamous cell carcinoma ?

a) Psammoma bodies

b) Keratin pearls and intercellular bridges

c) Reed-Sternberg cells

d) Glandular formations

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Category: NHPC , BMLT

21. The purpose of mounting media in slide preparation is to :

a) Enhance staining

b) Remove wax

c) Permanently preserve and clarify tissue sections

d) Dehydrate tissues

22 / 29

Category: NHPC , BMLT

22. A positive direct Coombs test indicates :

a) Hemophilia A

b) Autoimmune hemolytic anemia

c) Sickle cell disease

d) Thalassemia major

23 / 29

Category: NHPC , BMLT

23. A positive tuberculin skin test indicates :

a) Active tuberculosis

b) Latent TB infection

c) BCG vaccine failure

d) Antibody deficiency

24 / 29

Category: NHPC , BMLT

24. What is the primary purpose of formalin fixation in tissue processing ?

a) To dehydrate the tissue

b) To remove lipids

c) To prevent autolysis and preserve cellular structure

d) To enhance staining affinity

25 / 29

Category: NHPC , BMLT

25. ITP (Immune Thrombocytopenic Purpura) is characterized by :

a) Prolonged PT

b) Decreased megakaryocytes in bone marrow

c) Autoantibodies against platelets

d) Splenomegaly

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Category: NHPC , BMLT

26. Rheumatoid factor (RF) is typically an autoantibody against :

a) Fc region of IgG

b) Cyclic citrullinated peptide

c) Nuclear antigens

d) Cardiolipin

27 / 29

Category: NHPC , BMLT

27. The primary purpose of a cryostat is to :

a) Fix tissues rapidly

b) Cut frozen tissue sections

c) Embed tissues in paraffin

d) Stain slides automatically

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Category: NHPC , BMLT

28. Which immunohistochemical marker is positive in most breast carcinomas ?

a) S-100

b) Cytokeratin

c) Vimentin

d) Desmin

29 / 29

Category: NHPC , BMLT

29. Decalcification of bone tissue is performed using :

a) Xylene

b) Ethanol

c) Nitric acid

d) Paraffin

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