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Created by Lab Test Academy

NHPC , Biochem Specialization

M.Sc Medical Biochemistry

Welcome to Our Mock Test for M.Sc Medical Biochemistry ! 🚀 A warm welcome to Lab Test Academy ! We're thrilled to guide you through this M.Sc Medical Biochemistry Mock Test experience.

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Category: NHPC , Biochem Specialization

1. Which of the following best represents the reference (normal) range for arterial pH?

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Category: NHPC , Biochem Specialization

2. Ketoacidosis in diabetes occurs due to :

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Category: NHPC , Biochem Specialization

3. Which enzyme deficiency is responsible for phenylketonuria (PKU) ?

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Category: NHPC , Biochem Specialization

4. The HMP shunt pathway primarily produces :

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Category: NHPC , Biochem Specialization

5. Creatinine is formed from the :

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Category: NHPC , Biochem Specialization

6. Which of the following will shift the O2 dissociation curve to the left ?

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Category: NHPC , Biochem Specialization

7. Von Gierke's disease (Type I GSD) results from deficiency in :

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Category: NHPC , Biochem Specialization

8. The Cori cycle involves interconversion between :

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Category: NHPC , Biochem Specialization

9. Which of the following conditions is associated with hypokalemia?

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Category: NHPC , Biochem Specialization

10. The key regulatory enzyme in glycogenolysis is :

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Category: NHPC , Biochem Specialization

11. Which of the statements below about serum urea is true?

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Category: NHPC , Biochem Specialization

12. A diabetic patient presents with pH 7.20, HCO₃⁻ 10 mmol/L, anion gap 25 mmol/L, and positive serum ketones. The NEXT critical test is :

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Category: NHPC , Biochem Specialization

13. Electrophoresis is defined as the migration of charged particles under the influence of :

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Category: NHPC , Biochem Specialization

14. Which statement regarding nephelometry is true ?

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Category: NHPC

15. Which of the following hormones promotes hyperglycemia ?

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Category: NHPC , Biochem Specialization

16. Identify the enzyme deficiency responsible for type 1 glycogen storage disease (von Gierke’s disease).

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Category: NHPC , Biochem Specialization

17. Point-of-care-tests (POCTs) for whole-blood glucose monitoring are based mainly on the use of :

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Category: NHPC , Biochem Specialization

18. Insulin's primary action on glycogen metabolism is to :

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Category: NHPC , Biochem Specialization

19. A serum sodium level of 142 mmol/L falls within which of the following reference ranges ?

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Category: NHPC , Biochem Specialization

20. Blood ammonia levels are usually measured in order to evaluate :

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Category: NHPC , Biochem Specialization

21. Hyperparathyroidism is most consistently associated with :

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Category: NHPC , Biochem Specialization

22. Which of the following quality control (QC) rules would be broken 1 out of 20 times by chance alone ?

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Category: NHPC , Biochem Specialization

23. Which measurement principle is employed in a vapor pressure osmometer ?

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Category: NHPC , Biochem Specialization

24. The reference electrode in blood gas/electrolyte analyzers maintains a constant :

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Category: NHPC , Biochem Specialization

25. Which of the following enzymes is activated by calcium ions ?

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Category: NHPC , Biochem Specialization

26. Which compound is commonly used in chemiluminescent reactions in diagnostics ?

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Category: NHPC , Biochem Specialization

27. Renal glycosuria is characterized by :

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Category: NHPC , Biochem Specialization

28. Which of the following plots is best for detecting all types of QC errors ?

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Category: NHPC , Biochem Specialization

29. A urine protein:creatinine ratio of 5.6 indicates :

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Category: NHPC , Biochem Specialization

30. Which of the following statements about cortisol in Cushing’s syndrome is true ?

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Category: NHPC , Biochem Specialization

31. When sterilizing empty glassware like pipettes and beakers that are heat-stable and moisture-sensitive, the MOST appropriate equipment is a :

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Category: NHPC , Biochem Specialization

32. Which of the following conditions is associated with hypernatremia ?

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Category: NHPC , Biochem Specialization

33. Which of the following assays is recommended as a screening test for colorectal cancer in persons over 50 years old ?

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Category: NHPC , Biochem Specialization

34. What is a major benefit of Electrochemiluminescence Immunoassay (ECLIA) ?

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Category: NHPC , Biochem Specialization

35. Which TCA cycle enzyme is inhibited by ATP ?

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Category: NHPC , Biochem Specialization

36. Prolonged APTT not corrected by mixing studies suggests :

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Category: NHPC , Biochem Specialization

37. Blood sample collection time for peak drug levels :

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Category: NHPC , Biochem Specialization

38. Bilirubin is transported from reticuloendothelial cells to the liver by :

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Category: NHPC , Biochem Specialization

39. Which of the following is associated with low serum iron and high total iron-binding capacity (TIBC)?

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Category: NHPC , Biochem Specialization

40. Which type of cancer is associated with the highest level of AFP ?

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Category: NHPC , Biochem Specialization

41. Pyruvate dehydrogenase complex requires all EXCEPT :

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Category: NHPC , Biochem Specialization

42. A patient’s blood gas results are: pH = 7.50 P CO2 = 55 mm Hg HCO3– = 40 mmol/L , These results indicate :

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Category: NHPC , Biochem Specialization

43. In the liver, bilirubin is conjugated by the addition of :

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Category: NHPC , Biochem Specialization

44. What is a major advantage of chemiluminescent assays over photoluminescent assays ?

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Category: NHPC , Biochem Specialization

45. Which of the following conditions is cause for rejecting an analytical run ?

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Category: NHPC , Biochem Specialization

46. Which of the following is characteristic of type 1 diabetes mellitus?

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Category: NHPC , Biochem Specialization

47. The onset of menopause is usually associated with what hormone changes ?

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Category: NHPC , Biochem Specialization

48. The classic tetrad of nephrotic syndrome includes all EXCEPT :

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Category: NHPC , Biochem Specialization

49. HbA1c reflects average blood glucose levels over :

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Category: NHPC , Biochem Specialization

50. Classic galactosemia is caused by deficiency in :

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Category: NHPC , Biochem Specialization

51. Hypoglycemia in alcoholism occurs due to :

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Category: NHPC , Biochem Specialization

52. What component of a freezing point osmometer measures the sample temperature ?

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Category: NHPC , Biochem Specialization

53. Which enzyme is responsible for the conjugation of bilirubin ?

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Category: NHPC , Biochem Specialization

54. In a suspected infectious mononucleosis (IM) case, which test helps confirm the diagnosis ?

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Category: NHPC , Biochem Specialization

55. A core advantage of laboratory automation is :

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Category: NHPC , Biochem Specialization

56. Select the most appropriate adult reference range for fasting blood glucose.

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Category: NHPC , Biochem Specialization

57. Which specimen is the sample of choice for lead screening ?

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Category: NHPC , Biochem Specialization

58. Hereditary Fructose Intolerance (HFI) results from a deficiency in :

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Category: NHPC , Biochem Specialization

59. Which instrument is primarily used to detect chemiluminescence in the lab ?

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Category: NHPC , Biochem Specialization

60. Urea concentration is calculated from the BUN by multiplying by a factor of :

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Category: NHPC , Biochem Specialization

61. Which of the following lab findings is typical in alcoholic liver disease ?

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Category: NHPC , Biochem Specialization

62. Turbidimetry differs from nephelometry in that it measures :

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Category: NHPC , Biochem Specialization

63. Which formula correctly describes the relationship between absorbance and %T ?

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Category: NHPC , Biochem Specialization

64. Which of the following results falls within the diagnostic criteria for diabetes mellitus ?

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Category: NHPC , Biochem Specialization

65. Which support medium can be used to determine the molecular weight of a protein ?

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Category: NHPC , Biochem Specialization

66. In acute MI, cardiac troponin rises detectably in serum within :

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Category: NHPC , Biochem Specialization

67. In real-time PCR, what value is needed in order to determine the threshold ?

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Category: NHPC , Biochem Specialization

68. Upon which principle is the biuret method based ?

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Category: NHPC , Biochem Specialization

69. Which of the following is the best analyte to monitor for recurrence of ovarian cancer ?

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Category: NHPC , Biochem Specialization

70. Which of the following represents the Henderson–Hasselbalch equation as applied to blood pH?

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Category: NHPC , Biochem Specialization

71. A patient’s BUN is 60 mg/dL and serum creatinine is 3.0 mg/dL. These results suggest :

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Category: NHPC , Biochem Specialization

72. Which tumor marker is associated with cancer of the urinary bladder ?

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Category: NHPC , Biochem Specialization

73. Which of the following tumor markers is classified as a tumor suppressor gene ?

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Category: NHPC , Biochem Specialization

74. Which formula provides the best estimate of serum TIBC ?

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Category: NHPC , Biochem Specialization

75. A rising PSA level in a 65-year-old male post-prostatectomy suggests :

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Category: NHPC , Biochem Specialization

76. Which of the following is the most common cause of Cushing’s syndrome ?

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Category: NHPC , Biochem Specialization

77. Which hormone is hyperglycemic ?

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Category: NHPC , Biochem Specialization

78. Which of the following is the primary energy source for chemiluminescence ?

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Category: NHPC , Biochem Specialization

79. Which condition is associated with the lowest percent saturation of transferrin ?

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Category: NHPC , Biochem Specialization

80. Fluoride inhibits glycolysis by targeting which enzyme ?

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Category: NHPC , Biochem Specialization

81. Which of the following laboratory results is usually associated with cystic fibrosis ?

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Category: NHPC , Biochem Specialization

82. Which enzyme deficiency causes lactose intolerance ?

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Category: NHPC , Biochem Specialization

83. Deficiency of which enzyme causes Essential Pentosuria ?

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Category: NHPC , Biochem Specialization

84. Which of the following biochemical processes is promoted by insulin ?

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Category: NHPC , Biochem Specialization

85. Total ATP from complete aerobic glucose oxidation is :

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Category: NHPC , Biochem Specialization

86. Cholesterol esterase is used in enzymatic assays to :

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Category: NHPC , Biochem Specialization

87. Chronic alcohol consumption causes lactic acidosis by :

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Category: NHPC , Biochem Specialization

88. For long-term (24-72 hour) incubation of cell cultures requiring a highly stable temperature (±0.1°C), 5% CO₂, and high humidity, the MOST suitable equipment is a:

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Category: NHPC , Biochem Specialization

89. Which cardiac biomarker rises earliest after myocardial infarction (MI) ?

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Category: NHPC , Biochem Specialization

90. Which of the following is the primary mechanism for vasopressin (ADH) release ?

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Category: NHPC , Biochem Specialization

91. Uric acid is derived from the :

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Category: NHPC , Biochem Specialization

92. A lab measures total bilirubin by the Jendrassik–Grof bilirubin method with sample blanking. What would be the effect of moderate hemolysis on the test result ?

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Category: NHPC , Biochem Specialization

93. In diabetes, cataract formation is linked to the polyol pathway due to :

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Category: NHPC , Biochem Specialization

94. Urea is produced from :

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Category: NHPC , Biochem Specialization

95. External Quality Control (EQC) programs primarily assess :

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Category: NHPC , Biochem Specialization

96. Hyperalbuminemia is caused by :

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Category: NHPC , Biochem Specialization

97. A 35-year-old female presents with joint stiffness. Lab results show low albumin and anemia. What is the most likely diagnosis ?

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Category: NHPC , Biochem Specialization

98. Which statement regarding creatinine is true ?

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Category: NHPC , Biochem Specialization

99. What is the primary clinical utility of measuring CEA ?

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Category: NHPC , Biochem Specialization

100. The net ATP yield from anaerobic glycolysis per glucose molecule is :

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