Albumin Creatinine Ratio (ACR) Calculator

Calculate urine Albumin-to-Creatinine Ratio (ACR) from a spot urine sample and classify albuminuria severity per KDIGO categories — with instant interpretation.

Enter urine values

Use a first-morning or random spot urine sample. Tap the unit badge on Creatinine to switch mg/dL ⇆ mmol/L.

Switch to mg/dL if your lab reports albumin that way.

Albumin-Creatinine Ratio

– mg/g

 

–
A1 Normal A2 Moderate A3 Severe
Scale capped for display at 500 mg/g. A single elevated result should be confirmed on a repeat sample before diagnosing persistent albuminuria.

KDIGO Albuminuria Categories

A1 — Normal to Mildly Increased

<30 mg/g

(<3 mg/mmol)

Normal / physiological range

A2 — Moderately Increased

30–300 mg/g

(3–30 mg/mmol)

Formerly "microalbuminuria"

A3 — Severely Increased

>300 mg/g

(>30 mg/mmol)

Formerly "macroalbuminuria"

Formula

ACR (mg/mmol) = Urine Albumin (mg/L) ÷ Urine Creatinine (mmol/L) ACR (mg/g) = ACR (mg/mmol) × 8.84

About the Albumin-Creatinine Ratio

The urine ACR uses a spot urine sample to estimate 24-hour albumin excretion without the inconvenience of a timed collection. Dividing urine albumin by urine creatinine corrects for variation in urine concentration between samples, making a random spot sample almost as reliable as a 24-hour collection for most clinical purposes.

Clinical significance

  • ACR is a core component of KDIGO chronic kidney disease (CKD) staging, combined with eGFR to assess CKD risk category
  • Elevated albuminuria is an early, sensitive marker of diabetic and hypertensive kidney damage, often preceding a fall in eGFR
  • Persistent albuminuria (confirmed on 2 of 3 samples over 3–6 months) is more clinically significant than a single elevated value
  • Higher ACR is independently associated with increased cardiovascular risk, not just renal risk

Causes of transient (non-pathological) elevation

  • Vigorous exercise in the preceding 24 hours
  • Urinary tract infection or fever
  • Uncontrolled hyperglycemia or marked hypertension at time of sampling
  • Menstruation or heavy vaginal discharge contaminating the sample
  • Heart failure decompensation

Best practice for sample collection

  • A first-morning void is preferred; random spot samples are acceptable if first-morning isn't practical
  • Avoid testing during acute illness, heavy exercise, or menstruation where possible
  • A confirmed elevated ACR should prompt evaluation of eGFR, blood pressure, and glycemic control as part of a full CKD workup
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